Quantitative phase imaging of arthropods

Quantitative Phase Imaging

Quantitative Phase Shift Variance Imaging

Molecular ultrasound imaging is based on the detection of contrast agents (microbubbles) targeted to disease specific receptors in the vasculature. By quantifying the amount of the adherent microbubbles a change in the expression of these receptors and thus the disease development can be assessed. Quantification of microbubbles from ultrasound images in vivo was thus far mainly performed by ana...

Quantitative phase measurement in coherent diffraction imaging.

We demonstrate high spatial resolution phase retrieval of a non-periodic gold nano-structure using the method of Fresnel coherent diffractive imaging. The result is quantitative to better than 10% and does not rely on any a priori knowledge of the sample.

Illumination coherence engineering and quantitative phase imaging.

Partially coherent illumination provides significant advantages such as speckle-free imaging and enhanced optical sectioning in optical microscopy. The knowledge of the spatial and temporal coherence is crucial to obtain accurate quantitative phase imaging (QPI) of specimens such as live cells, micrometer-sized particles, etc. In this Letter, we propose a novel technique for illumination cohere...

Quantitative phase imaging with partially coherent illumination.

In this Letter, we formulate a mathematical model for predicting experimental outcomes in quantitative phase imaging (QPI) when the illumination field is partially spatially coherent. We derive formulae that apply to QPI and discuss expected results for two classes of QPI experiments: common path and traditional interferometry, under varying degrees of spatial coherence. In particular, our resu...